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MOTS-c

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UP-MOTSC
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Molecular FormulaC101H152N28O22S2
CAS Number1627580-64-6
Molar Mass2174.6 g/mol
Amino Acid SequenceH-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH
SynonymsMitochondrial Open Reading Frame of the 12S rRNA-c, MOTS-c peptide, Mitochondrial-Derived Peptide MOTS-c
SolubilityWater-soluble
Organoleptic ProfileWhite to off-white powder
CompositionLyophilized powder

MOTS-c is studied in laboratory and preclinical research as a model peptide for investigating mitochondrial and cellular pathways. Typical research applications include:

  • Testing mitochondrial responses: Researchers measure respiration, ATP production, and other energy-related outputs.
  • Cell-based assays: Monitoring how cells react to controlled stressors or metabolic challenges.
  • Experimental modeling: Applying MOTS-c in vitro or in vivo to observe pathway interactions under precise conditions.
  • Metabolic pathway research: Studies investigate how MOTS-c interacts with molecular pathways involved in energy regulation, glucose metabolism, and lipid signaling in experimental models.
  • Mitochondrial biology: Laboratory experiments examine mitochondrial function, dynamics, and respiration to understand cellular energy processes.
  • Cell stress and cytoprotection research: Researchers explore how cells respond to oxidative stress and other controlled stressors in the presence of MOTS-c.
  • Exercise and muscle metabolism studies: Mechanistic studies assess skeletal muscle adaptation and energy pathways in experimental settings.
  • Age-related cellular studies: MOTS-c is studied in models of age-related cellular changes and mitochondrial function.
  • Inflammatory signaling: Some preclinical work investigates how MOTS-c interacts with pathways linked to cellular signaling and inflammation under laboratory conditions.

Based on the available preclinical data, the most common side effects associated with MOTS-c treatment include:

  • Injection site reactions (redness, swelling) in animal models
  • Transient changes in blood glucose levels during metabolic studies
  • Mild gastrointestinal effects observed in preclinical research

Note: The safety profile of MOTS-c has not been fully established, and further clinical studies are needed to fully evaluate the potential for side effects and long-term safety of MOTS-c in mammals.

MOTS-c is a synthetic mitochondrial-derived peptide used in controlled laboratory investigations. It supports studies into mitochondrial signaling, metabolic pathways, and cellular energy regulation. Designed strictly for research use, it enables experiments focused on mitochondrial biology, metabolic function, and peptide stability in experimental settings. This product is intended solely for in vitro and preclinical research use. No conclusions can be drawn regarding safety, efficacy, or therapeutic use in humans.

Certificate of Analysis - MOTS-c 10mg

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All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. Neither the products described nor the company are intended to diagnose, treat, cure, or prevent any disease.

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